Insider Transactions

Date	Name	Title	Type	Shares Traded	Price Range
03/22/10	janse michael a	Officer	Option Execute	2,653	3.75
09/14/09	janse michael a	Officer	Option Execute	2,653	3.75
11/16/10	janse michael a	Officer	Option Execute	2,653	3.75
10/12/10	janse michael a	Officer	Option Execute	2,653	3.75
12/09/10	janse michael a	Officer	Option Execute	2,653	3.75
09/15/10	janse michael a	Officer	Option Execute	2,653	3.75
09/09/10	janse michael a	Officer	Option Execute	2,653	3.75
12/16/09	Wolfe, Daniel B. Ph.d.	Officer	Option Execute	2,667	3.75
08/12/11	lanza lucio	Director	Automatic Buy	2,740	4.31
12/17/07	Fletcher, Dugald A.	Director	Buy	2,767	8.40 - 8.49
08/12/11	Bauman, Phillip A. M.d.	Director	Automatic Buy	2,860	4.31
10/10/07	Jamison, Douglas W.	Officer	Automatic Sell	2,900	11.00 - 11.07
12/31/12	burns robert stephen	Officer	Disposition (Non Open Market)	2,920	3.30
10/09/07	Wolfe, Daniel B. Ph.d.	Officer	Automatic Sell	2,946	11.00
03/24/08	Roberts, James E.	Director	Buy	2,950	6.55 - 6.71
10/10/07	Jamison, Douglas W.	Officer	Option Execute	2,973	10.11
10/09/07	Wolfe, Daniel B. Ph.d.	Officer	Option Execute	2,984	10.11
06/03/10	Bauman, Phillip A. M.d.	Director	Buy	3,000	4.31 - 4.38
05/02/11	Egan, Patricia N. Cpa	Officer	Automatic Sell	3,000	5.14
05/02/11	Egan, Patricia N. Cpa	Officer	Option Execute	3,000	4.46
Showing 281-300 of 413 transactions Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21  See Previous 20 | See Next 20

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